enhancer drug
Evidence from:
primary |
all sources
Related entities (13)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| DNase hypersensitivity | interacts_with | enhancer | — | 1 |
| enhancer | expressed_in | blood cell type | — | 1 |
| enhancer | associated_with | Gm12878 | — | 1 |
| enhancer | associated_with | H3K27ac | — | 1 |
| enhancer | associated_with | H3K4me1 | — | 1 |
| enhancer | associated_with | H3K4me2 | — | 1 |
| enhancer | interacts_with | promoter | 0.05 | 1 |
| H3K27ac | associated_with | enhancer | — | 1 |
| H3K27ac | interacts_with | enhancer | — | 1 |
| H3K4me1 | associated_with | enhancer | — | 1 |
| H3K4me1 | interacts_with | enhancer | — | 1 |
| RNA polymerase II | interacts_with | enhancer | — | 1 |
| rs1409568 | associated_with | enhancer | — | 1 |
Mentioned in (26)
Papers in which this entity is mentioned.
- Annotating the genome at single-nucleotide resolution with DNA foundation models. (2025)
- Nucleotide Transformer: building and evaluating robust foundation models for human genomics. (2025)
- Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
- Validation of the new EPIC DNA methylation microarray (900K EPIC v2) for high-throughput profiling of the human DNA methylome. (2023)
- Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence. (2021)
- Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
- PEREGRINE: A genome-wide prediction of enhancer to gene relationships supported by experimental evidence. (2020)
- Transcriptomic signatures across human tissues identify functional rare genetic variation. (2020)
- Genome-wide DNA methylation comparison between live human brain and peripheral tissues within individuals. (2019)
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
- Genome-wide association study identifies a novel locus for cannabis dependence. (2018)
- Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. (2018)
- Genetic effects on gene expression across human tissues. (2017)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association. (2016)
- Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
- Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
- Epigenomics and the structure of the living genome. (2015)
- An atlas of active enhancers across human cell types and tissues. (2014)
- MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
- DNA methylation signatures link prenatal famine exposure to growth and metabolism. (2014)
- Global epigenomic reconfiguration during mammalian brain development. (2013)
- Fine tuning of craniofacial morphology by distant-acting enhancers. (2013)
- Landscape of transcription in human cells. (2012)
- An integrated encyclopedia of DNA elements in the human genome. (2012)
- Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. (2009)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| enhancer | drug | 15 | 20 |
| enhancers | drug | 12 | 13 |
| active enhancers | drug | 3 | 3 |
| active enhancer | drug | — | — |