KRAS gene

Aliases

K-ras, Ras

External links

NCBI Gene · Ensembl · GeneCards · UniProt

No related entities found.

Mentioned in (74)

Papers in which this entity is mentioned.

• Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers. (2025)
• Chromosomal instability as a driver of cancer progression. (2025)
• Three-dimensional genome landscape of primary human cancers. (2025)
• Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. (2025)
• MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC. (2025)
• Molecular profiling of 888 pediatric tumors informs future precision trials and data-sharing initiatives in pediatric cancer. (2024)
• Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning. (2024)
• Insights for precision oncology from the integration of genomic and clinical data of 13,880 tumors from the 100,000 Genomes Cancer Programme. (2024)
• Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology. (2024)
• Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma. (2023)
• Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors. (2023)
• Machine learning for genetics-based classification and treatment response prediction in cancer of unknown primary. (2023)
• Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA. (2022)
• Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids. (2022)
• Single-cell genomic variation induced by mutational processes in cancer. (2022)
• Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers. (2022)
• Evaluating the transcriptional fidelity of cancer models. (2021)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. (2021)
• : batch effect adjustment for RNA-seq count data. (2020)
• Inferring structural variant cancer cell fraction. (2020)
• Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma. (2020)
• Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA. (2020)
• Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. (2019)
• CHASMplus Reveals the Scope of Somatic Missense Mutations Driving Human Cancers. (2019)
• How I diagnose and manage Philadelphia chromosome-like acute lymphoblastic leukemia. (2019)
• Assessment of tumor mutation burden calculation from gene panel sequencing data. (2019)
• RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues. (2019)
• Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
• Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. (2018)
• Detection of Somatic Structural Variants Enables Quantification and Characterization of Circulating Tumor DNA in Children With Solid Tumors. (2018)
• Quantification of subclonal selection in cancer from bulk sequencing data. (2018)
• Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
• Comprehensive Characterization of Cancer Driver Genes and Mutations. (2018)
• Genome doubling shapes the evolution and prognosis of advanced cancers. (2018)
• The Immune Landscape of Cancer. (2018)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
• Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations. (2018)
• Copy number signatures and mutational processes in ovarian carcinoma. (2018)
• OncoKB: A Precision Oncology Knowledge Base. (2017)
• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
• Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
• Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. (2017)
• Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients. (2017)
• Copy-number signatures and mutational processes in ovarian carcinoma (2017)
• Clinical Assessment and Diagnosis of Germline Predisposition to Hematopoietic Malignancies: The University of Chicago Experience. (2017)
• An open access pilot freely sharing cancer genomic data from participants in Texas. (2016)
• Integrated digital error suppression for improved detection of circulating tumor DNA. (2016)
• Fragment Length of Circulating Tumor DNA. (2016)
• The clinical trial landscape in oncology and connectivity of somatic mutational profiles to targeted therapies. (2016)
• Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
• Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
• Recurrent somatic mutations in regulatory regions of human cancer genomes. (2015)
• Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia. (2015)
• MBASED: allele-specific expression detection in cancer tissues and cell lines. (2014)
• RADIA: RNA and DNA integrated analysis for somatic mutation detection. (2014)
• Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. (2014)
• An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. (2014)
• Clonal evolution in hematological malignancies and therapeutic implications. (2014)
• Cancer genome landscapes. (2013)
• Clinical whole-exome sequencing for the diagnosis of mendelian disorders. (2013)
• A simple consensus approach improves somatic mutation prediction accuracy. (2013)
• A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. (2013)
• Emerging landscape of oncogenic signatures across human cancers. (2013)
• Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. (2013)
• Computational approaches to identify functional genetic variants in cancer genomes. (2013)
• Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
• The genomic landscape of hypodiploid acute lymphoblastic leukemia. (2013)
• LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7. (2013)
• High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. (2012)
• Molecular genetics of B-precursor acute lymphoblastic leukemia. (2012)
• Patient-derived tumour xenografts as models for oncology drug development. (2012)
• GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. (2011)
• DNA copy number, including telomeres and mitochondria, assayed using next-generation sequencing. (2010)
• Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum. (2009)

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