PSEN2 gene
Evidence from:
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all sources
Related entities (8)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| PSEN2 | risk_factor_for | Alzheimer's disease | — | 1 |
| PSEN2 | risk_factor_for | Alzheimer’s disease | — | 1 |
| PSEN2 | associated_with | Alzheimer’s disease | — | 1 |
| PSEN2 | associated_with | Aβ42/Aβ40 ratio | — | 1 |
| PSEN2 | risk_factor_for | Early-onset Alzheimer’s disease | — | 1 |
| PSEN2 | risk_factor_for | fAD | — | 1 |
| PSEN2 | protective_against | plaque | — | 1 |
| PSEN2 | risk_factor_for | plaque | — | 1 |
Mentioned in (18)
Papers in which this entity is mentioned.
- Pitfalls of predicting age-related traits by polygenic risk scores. (2023)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- Interpretation of risk loci from genome-wide association studies of Alzheimer's disease. (2020)
- Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017)
- Three Dimensional Human Neuro-Spheroid Model of Alzheimer's Disease Based on Differentiated Induced Pluripotent Stem Cells. (2016)
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
- Evaluating historical candidate genes for schizophrenia. (2015)
- Heritability and genomics of gene expression in peripheral blood. (2014)
- New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. (2014)
- Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
- Amyloid pathway-based candidate gene analysis of [(11)C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort. (2012)
- Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease. (2011)
- Apolipoprotein E: from lipid transport to neurobiology. (2011)
- Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. (2011)
- Transgenic mouse models of Alzheimer's disease. (2010)
- Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. (2009)
- Network analysis of intrinsic functional brain connectivity in Alzheimer's disease. (2008)
- COGA phenotypes and linkages on chromosome 2. (2005)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| psen2 | gene | 17 | 25 |
| ps2 | gene | 2 | 2 |
| presenilin 2 | gene | — | — |
| presenilin-2 | gene | — | — |