Klb gene
Evidence from:
primary |
all sources
Related entities (24)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Fgf21 | targets | Klb | — | 1 |
| Fgf21 | interacts_with | Klb | — | 3 |
| FGFR1 | interacts_with | Klb | — | 1 |
| Klb | associated_with | alcohol | — | 6 |
| Klb | protective_against | alcohol preference | — | 1 |
| Klb | associated_with | alcohol-related phenotypes | — | 2 |
| Klb | associated_with | Alcohol Use Disorders Identification Test | — | 1 |
| Klb | associated_with | AUDIT | — | 1 |
| Klb | biomarker_for | AUDIT | — | 1 |
| Klb | biomarker_for | AUDIT-C | — | 1 |
| Klb | associated_with | AUDIT-C | — | 3 |
| Klb | expressed_in | brain | — | 1 |
| Klb | associated_with | drinks per week | — | 1 |
| Klb | interacts_with | Fgf21 | — | 2 |
| Klb | interacts_with | FGFR1 | — | 1 |
| Klb | associated_with | glucose lowering | — | 1 |
| Klb | biomarker_for | neurodegeneration | 0.017 | 1 |
| Klb | associated_with | PAU | — | 1 |
| Klb | risk_factor_for | PAU | — | 1 |
| Klb | associated_with | UKB | — | 1 |
| Klb | biomarker_for | UKB | — | 1 |
| Klb | expressed_in | wild-type mice | — | 1 |
| rs11940694 | associated_with | Klb | 0.38 | 1 |
| ZBTB16 | regulates | Klb | — | 1 |
Mentioned in (15)
Papers in which this entity is mentioned.
- Clinical, genomic, and neurophysiological correlates of lifetime suicide attempts among individuals with alcohol dependence. (2024)
- Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder. (2024)
- Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023)
- Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts. (2022)
- Parsing genetically influenced risk pathways: genetic loci impact problematic alcohol use via externalizing and specific risk. (2022)
- Gene-based polygenic risk scores analysis of alcohol use disorder in African Americans. (2022)
- Genetics of substance use disorders in the era of big data. (2021)
- Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020)
- Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations. (2019)
- Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts. (2019)
- Human Genetics of Addiction: New Insights and Future Directions. (2018)
- Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017)
- Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017)
- Stressed Liver and Muscle Call on Adipocytes with FGF21. (2013)
- FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. (2012)
Merged raw entities (5)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| klb | gene | 15 | 52 |
| beta-klotho | gene | — | — |
| betaklotho | gene | — | — |
| klotho beta | gene | — | — |
| β-klotho | gene | — | — |