NP-40 drug

Aliases

0.02% NP-40, Nonidet P-40

External links

DrugBank · PubChem

Related entities (1)

Mentioned in (54)

Papers in which this entity is mentioned.

• Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics. (2026)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing. (2025)
• Global impact of unproductive splicing on human gene expression. (2024)
• Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. (2024)
• Alcohol blunts pregnancy-mediated insulin resistance and reduces fetal brain glucose despite elevated fetal gluconeogenesis, and these changes associate with fetal weight outcomes. (2023)
• Joint single-cell measurements of nuclear proteins and RNA in vivo. (2021)
• Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
• Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. (2021)
• Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
• Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
• PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome. (2020)
• Genetic compensation triggered by mutant mRNA degradation. (2019)
• Rapid and reversible suppression of ALT by DAXX in osteosarcoma cells. (2019)
• Alcohol metabolism contributes to brain histone acetylation. (2019)
• Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
• Mental Illnesses-Associated Fxr1 and Its Negative Regulator Gsk3β Are Modulators of Anxiety and Glutamatergic Neurotransmission. (2018)
• Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
• Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. (2017)
• Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. (2017)
• Impact of cytosine methylation on DNA binding specificities of human transcription factors. (2017)
• Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin. (2016)
• Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
• Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. (2016)
• CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015)
• Effect of lipid raft disruption on ethanol inhibition of l1 adhesion. (2014)
• Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. (2013)
• LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype. (2013)
• Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. (2013)
• Dysregulation of the long non-coding RNA transcriptome in a Rett syndrome mouse model. (2013)
• Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. (2013)
• Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. (2012)
• Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. (2012)
• A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. (2011)
• Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. (2011)
• CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. (2011)
• Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. (2010)
• The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
• Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
• Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. (2009)
• Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. (2009)
• Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation. (2009)
• A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog. (2009)
• Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). (2009)
• Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans. (2008)
• Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. (2007)
• PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
• Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. (2006)
• Molecular mechanisms of Sonic hedgehog mutant effects in holoprosencephaly. (2005)
• Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (2005)
• Layer specification of transplanted interneurons in developing mouse neocortex. (2003)
• Mouse Af9 is a controller of embryo patterning, like Mll, whose human homologue fuses with Af9 after chromosomal translocation in leukemia. (2002)
• Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. (2001)
• EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes. (1998)

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