ATM gene
Evidence from:
primary |
all sources
Related entities (9)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ATM | regulates | CHEK2 | — | 1 |
| ATM | regulates | DNMT1 | — | 1 |
| ATM | regulates | EZH2 | — | 1 |
| ATM | regulates | HDAC4 | — | 1 |
| ATM | protective_against | iPSCs | — | 1 |
| ATM | associated_with | neurodegeneration | — | 1 |
| ATM | regulates | RB1 | — | 1 |
| ATM | regulates | Tet1 | — | 1 |
| ATM | regulates | TP53 | 3.46e-05 | 1 |
Mentioned in (46)
Papers in which this entity is mentioned.
- Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort. (2026)
- Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States. (2025)
- FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
- Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy. (2024)
- Heritable defects in telomere and mitotic function selectively predispose to sarcomas. (2023)
- RNA splicing dysregulation and the hallmarks of cancer. (2023)
- Integrating molecular profiles into clinical frameworks through the Molecular Oncology Almanac to prospectively guide precision oncology. (2021)
- Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
- Therapeutic Implications of Germline Testing in Patients With Advanced Cancers. (2021)
- Pan-cancer analysis of whole genomes. (2020)
- Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
- The GenomeAsia 100K Project enables genetic discoveries across Asia. (2019)
- Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
- Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
- Mutational processes shape the landscape of TP53 mutations in human cancer. (2018)
- Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. (2018)
- Tumor fraction in cell-free DNA as a biomarker in prostate cancer. (2018)
- Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
- Molecular profiling and sequential somatic mutation shift in hypermutator tumours harbouring POLE mutations. (2018)
- Patterns and mechanisms of structural variations in human cancer. (2018)
- HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. (2017)
- Universal Patterns of Selection in Cancer and Somatic Tissues. (2017)
- Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
- Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. (2017)
- Copy-number signatures and mutational processes in ovarian carcinoma (2017)
- Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences. (2016)
- Integrative clinical genomics of advanced prostate cancer. (2015)
- Germline Mutations in Predisposition Genes in Pediatric Cancer. (2015)
- Spontaneous ATM Gene Reversion in A-T iPSC to Produce an Isogenic Cell Line. (2015)
- Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine. (2014)
- Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. (2014)
- Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
- Clonal evolution in hematological malignancies and therapeutic implications. (2014)
- Exon identity crisis: disease-causing mutations that disrupt the splicing code. (2014)
- Ewing sarcoma protein: a key player in human cancer. (2013)
- RNA splicing: a new player in the DNA damage response. (2013)
- Pan-cancer patterns of somatic copy number alteration. (2013)
- BRCA1 and BRCA2: different roles in a common pathway of genome protection. (2011)
- Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development. (2011)
- Functional consequences of developmentally regulated alternative splicing. (2011)
- Linking functional decline of telomeres, mitochondria and stem cells during ageing. (2010)
- Gene--environment-wide association studies: emerging approaches. (2010)
- Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. (2009)
- Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF). (2009)
- MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. (2008)
Merged raw entities (7)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| atm | gene | 46 | 170 |
| ataxia telangiectasia mutated | gene | — | — |
| at m | gene | — | — |
| atm gene | gene | — | — |
| atm protein | gene | — | — |
| p-atm | gene | — | — |
| phospho-atm | gene | — | — |