liver injury phenotype
Evidence from:
primary |
all sources
Related entities (10)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| acetaldehyde | risk_factor_for | liver injury | — | 1 |
| alcohol | risk_factor_for | liver injury | — | 1 |
| chronic alcoholism | risk_factor_for | liver injury | — | 1 |
| CYP2E1 | risk_factor_for | liver injury | — | 1 |
| ethanol group | risk_factor_for | liver injury | — | 1 |
| Fgf21 | associated_with | liver injury | — | 1 |
| liver injury | regulates | PPARG | — | 1 |
| oxidative stress | risk_factor_for | liver injury | — | 1 |
| PPARα−/− mice | risk_factor_for | liver injury | — | 1 |
| ROS | risk_factor_for | liver injury | — | 1 |
Mentioned in (31)
Papers in which this entity is mentioned.
- Evidence and Perspectives for Choline Supplementation during Parenteral Nutrition-A Narrative Review. (2024)
- Oral supplementation of choline attenuates the development of alcohol-related liver disease (ALD). (2024)
- A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice. (2024)
- Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
- Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders. (2022)
- Pathogenesis of Alcohol-Associated Fatty Liver: Lessons From Transgenic Mice. (2022)
- Beneficial Effects of Betaine: A Comprehensive Review. (2021)
- Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis. (2021)
- Prenatal choline supplementation during mouse pregnancy has differential effects in alcohol-exposed fetal organs. (2021)
- Alterations in Insulin Levels in Adults with Prenatal Alcohol Exposure. (2021)
- Computer-based alcohol reduction intervention for alcohol-using HIV/HCV co-infected Russian women in clinical care: study protocol for a randomized controlled trial. (2021)
- Postnatal choline supplementation selectively attenuates hippocampal microRNA alterations associated with developmental alcohol exposure. (2017)
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016)
- Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015)
- Stressed Liver and Muscle Call on Adipocytes with FGF21. (2013)
- Nutrition in pregnancy: the argument for including a source of choline. (2013)
- Zebrafish models of human liver development and disease. (2013)
- Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
- The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. (2011)
- Focus on: epigenetics and fetal alcohol spectrum disorders. (2011)
- The role of NOX enzymes in ethanol-induced oxidative stress and apoptosis in mouse embryos. (2010)
- The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
- The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
- Choline: an essential nutrient for public health. (2009)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. (2009)
- Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. (2007)
- Choline: critical role during fetal development and dietary requirements in adults. (2006)
- Modeling alcohol's effects on organs in animal models. (2000)
- The hormonal effects of alcohol use on the mother and fetus. (1998)
- Impairments of brain and behavior: the neurological effects of alcohol. (1997)
Merged raw entities (6)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| liver damage | phenotype | 19 | 37 |
| liver injury | phenotype | 16 | 27 |
| alcoholic liver injury | phenotype | 4 | 4 |
| ethanol-induced liver injury | phenotype | 3 | 4 |
| alcohol induced liver injury | phenotype | — | — |
| lps-induced liver injury | phenotype | — | — |