Akt gene
Evidence from:
primary |
all sources
Related entities (8)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Akt | expressed_in | cortex | — | 1 |
| Akt | regulates | Fgf21 | — | 1 |
| Akt | regulates | FoxO1 | — | 1 |
| Akt | regulates | FoxO3a | — | 1 |
| Akt | expressed_in | hippocampus | — | 1 |
| LY294002 | regulates | Akt | — | 1 |
| PI3K | regulates | Akt | — | 1 |
| serotonin | regulates | Akt | — | 1 |
Mentioned in (81)
Papers in which this entity is mentioned.
- Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
- Osteoclasts in Osteosarcoma: Mechanisms, Interactions, and Therapeutic Prospects. (2023)
- Towards understandings of serine/arginine-rich splicing factors. (2023)
- Rodent models in placental research. Implications for fetal origins of adult disease. (2022)
- Loss of tumor protein 53 protects against alcohol-induced facial malformations in mice and zebrafish. (2021)
- Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
- Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
- Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X. (2020)
- TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
- Transcriptome-Wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure. (2020)
- Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors. (2020)
- Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders. (2019)
- Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
- Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
- mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
- TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- Copy number signatures and mutational processes in ovarian carcinoma. (2018)
- OncoKB: A Precision Oncology Knowledge Base. (2017)
- Gene-environment interactions in development and disease. (2017)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
- Copy-number signatures and mutational processes in ovarian carcinoma (2017)
- Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers. (2016)
- Alcohol Use During Pregnancy is Associated with Specific Alterations in MicroRNA Levels in Maternal Serum. (2016)
- Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. (2016)
- The Genetics of Fetal Alcohol Spectrum Disorders. (2016)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
- Low Density Lipoprotein Receptor Related Proteins as Regulators of Neural Stem and Progenitor Cell Function. (2016)
- Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. (2015)
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015)
- Fetal Alcohol Spectrum Disorders: An Overview from the Glia Perspective. (2015)
- A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin. (2015)
- A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
- CtBP2 is an independent prognostic marker that promotes GLI1 induced epithelial-mesenchymal transition in hepatocellular carcinoma. (2015)
- Regulation of mTORC1 by PI3K signaling. (2015)
- Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance. (2015)
- 708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits. (2014)
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
- Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
- Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
- Cancer genome landscapes. (2013)
- Stressed Liver and Muscle Call on Adipocytes with FGF21. (2013)
- An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice. (2013)
- Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
- Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
- Pdgfra protects against ethanol-induced craniofacial defects in a zebrafish model of FASD. (2013)
- Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. (2013)
- Emerging landscape of oncogenic signatures across human cancers. (2013)
- Commonality in Down and fetal alcohol syndromes. (2013)
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. (2013)
- Novel mutations target distinct subgroups of medulloblastoma. (2012)
- Patient-derived tumour xenografts as models for oncology drug development. (2012)
- Teratogenic effects of thalidomide: molecular mechanisms. (2011)
- The role of zinc in the modulation of neuronal proliferation and apoptosis. (2010)
- Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
- Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. (2010)
- Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
- Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. (2009)
- Actions and interactions of alcohol and insulin-like growth factor-1 on female pubertal development. (2009)
- Effects of ethanol and ipsapirone on the expression of genes encoding anti-apoptotic proteins and an antioxidant enzyme in ethanol-treated neurons. (2009)
- Adrenomedullin signaling is necessary for murine lymphatic vascular development. (2008)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling. (2008)
- Platelet-derived growth factor receptor beta signaling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populations. (2008)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. (2003)
- Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. (2003)
- Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. (2002)
- Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
- Myelination is altered in insulin-like growth factor-I null mutant mice. (2002)
- Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. (2001)
- Measuring the thickness of the human cerebral cortex from magnetic resonance images. (2000)
- Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. (1995)
- In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. (1995)
Merged raw entities (5)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| akt | gene | 79 | 209 |
| akt | drug | 18 | 22 |
| akt kinases | gene | — | — |
| pkb | gene | — | — |
| protein kinase b | gene | — | — |