Trp53 gene
Evidence from:
primary |
all sources
Related entities (9)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| ethanol group | regulates | Trp53 | — | 1 |
| ROS | associated_with | Trp53 | — | 1 |
| SIRT1 | regulates | Trp53 | — | 1 |
| Telomeres | regulates | Trp53 | — | 1 |
| Trp53 | regulates | apoptosis | — | 1 |
| Trp53 | regulates | cellular senescence | — | 1 |
| Trp53 | regulates | Fgf21 | — | 1 |
| Trp53 | biomarker_for | multiple sclerosis | — | 1 |
| Trp53 | interacts_with | Trail | — | 1 |
Mentioned in (57)
Papers in which this entity is mentioned.
- Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models. (2026)
- Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships. (2026)
- Extrachromosomal DNA-Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma. (2025)
- Multigenerational cell tracking of DNA replication and heritable DNA damage. (2025)
- Tracing the evolution of single-cell 3D genomes in Kras-driven cancers. (2025)
- Gastrulation-stage alcohol exposure induces similar rates of craniofacial malformations in male and female C57BL/6J mice. (2024)
- Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells. (2024)
- Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma. (2023)
- Chronic oligodendrocyte injury in central nervous system pathologies. (2022)
- Integrated analysis of multimodal single-cell data. (2021)
- Evaluating the transcriptional fidelity of cancer models. (2021)
- Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
- Simultaneous single cell measurements of intranuclear proteins and gene expression (2021)
- Tead transcription factors differentially regulate cortical development. (2020)
- Emerging Roles of SRSF3 as a Therapeutic Target for Cancer. (2020)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- Designing combination therapies with modeling chaperoned machine learning. (2019)
- Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. (2018)
- OncoKB: A Precision Oncology Knowledge Base. (2017)
- PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
- A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
- Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice. (2015)
- MiR-125b protects against ethanol-induced apoptosis in neural crest cells and mouse embryos by targeting Bak 1 and PUMA. (2015)
- Comprehensive genomic profiles of small cell lung cancer. (2015)
- Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing. (2015)
- Fat-Dachsous signaling coordinates cartilage differentiation and polarity during craniofacial development. (2014)
- MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. (2014)
- CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. (2014)
- Effects of Acute Prenatal Exposure to Ethanol on microRNA Expression are Ameliorated by Social Enrichment. (2014)
- Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
- Stressed Liver and Muscle Call on Adipocytes with FGF21. (2013)
- Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. (2013)
- A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. (2013)
- An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. (2013)
- Microsatellites with macro-influence in ewing sarcoma. (2012)
- Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. (2012)
- A hippocampal insulin-growth factor 2 pathway regulates the extinction of fear memories. (2011)
- Functional consequences of developmentally regulated alternative splicing. (2011)
- Allele-specific copy number analysis of tumors. (2010)
- The role of zinc in the modulation of neuronal proliferation and apoptosis. (2010)
- Linking functional decline of telomeres, mitochondria and stem cells during ageing. (2010)
- Structural, metabolic, and functional brain abnormalities as a result of prenatal exposure to drugs of abuse: evidence from neuroimaging. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Fetal effects of psychoactive drugs. (2009)
- BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. (2009)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- Neuroimaging of children following prenatal drug exposure. (2009)
- MDM2 and MDM4: p53 regulators as targets in anticancer therapy. (2007)
- Choline: critical role during fetal development and dietary requirements in adults. (2006)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation. (2005)
- Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique. (2004)
- Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. (2003)
- Role of founder cell deficit and delayed neuronogenesis in microencephaly of the trisomy 16 mouse. (2000)
- Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: evidence from positron emission tomography studies with [11C]WIN-35,428. (1998)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| p53 | gene | 45 | 74 |
| trp53 | gene | 14 | 39 |