Tlr4 gene
Evidence from:
primary |
all sources
Related entities (20)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| amyloid β | interacts_with | Tlr4 | — | 1 |
| Cd14 | interacts_with | Tlr4 | — | 2 |
| CYP2E1 | regulates | Tlr4 | — | 1 |
| ethanol group | regulates | Tlr4 | — | 2 |
| human alcoholics | associated_with | Tlr4 | — | 1 |
| lipopolysaccharide | interacts_with | Tlr4 | — | 1 |
| LPS | interacts_with | Tlr4 | — | 1 |
| Myd88 | interacts_with | Tlr4 | — | 1 |
| NFκB | regulates | Tlr4 | — | 1 |
| SASH1 | interacts_with | Tlr4 | — | 1 |
| self-discipline | regulates | Tlr4 | — | 1 |
| Tlr4 | expressed_in | astrocytes | — | 1 |
| Tlr4 | expressed_in | brain tissue | — | 1 |
| Tlr4 | interacts_with | Cd14 | — | 1 |
| Tlr4 | interacts_with | LPS | — | 3 |
| Tlr4 | risk_factor_for | neuroinflammation | — | 1 |
| Tlr4 | expressed_in | orbitofrontal cortex | — | 1 |
| Tlr4 | expressed_in | peripheral blood monocytes | — | 1 |
| Tlr4 | regulates | PPARG | — | 1 |
| Tlr4 | regulates | TNF | — | 1 |
Mentioned in (43)
Papers in which this entity is mentioned.
- Concordance between male- and female-specific GWAS results helps define underlying genetic architecture of complex traits. (2025)
- Oral supplementation of choline attenuates the development of alcohol-related liver disease (ALD). (2024)
- Pathogenesis of Alcoholic Fatty Liver a Narrative Review. (2023)
- Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
- Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting. (2023)
- RNA splicing dysregulation and the hallmarks of cancer. (2023)
- Epigenetics in Alzheimer's Disease. (2022)
- Beneficial Effects of Betaine: A Comprehensive Review. (2021)
- Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. (2021)
- Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions. (2021)
- Neurotoxic reactive astrocytes induce cell death via saturated lipids. (2021)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- An enriched biosignature of gut microbiota-dependent metabolites characterizes maternal plasma in a mouse model of fetal alcohol spectrum disorder. (2021)
- Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
- ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing. (2020)
- Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations. (2020)
- Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity. (2020)
- Effects of chronic intermittent ethanol exposure and withdrawal on neuroblastoma cell transcriptome. (2020)
- Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
- Ethanol activates immune response in lymphoblastoid cells. (2019)
- Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders. (2018)
- The effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic network. (2017)
- Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders. (2017)
- Copy-number signatures and mutational processes in ovarian carcinoma (2017)
- Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD. (2016)
- Fetal Alcohol Spectrum Disorders: An Overview from the Glia Perspective. (2015)
- A review of the nonpressor and nonantidiuretic actions of the hormone vasopressin. (2015)
- Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. (2013)
- Circulating microRNAs in exosomes indicate hepatocyte injury and inflammation in alcoholic, drug-induced, and inflammatory liver diseases. (2012)
- Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response. (2012)
- Ethanol causes the redistribution of L1 cell adhesion molecule in lipid rafts. (2011)
- Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
- MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
- Effects of moderate drinking during pregnancy on placental gene expression. (2010)
- The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
- The opposite effects of acute and chronic alcohol on lipopolysaccharide-induced inflammation are linked to IRAK-M in human monocytes. (2009)
- Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src). (2009)
- Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009)
- 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| tlr4 | gene | 41 | 85 |
| toll-like receptor 4 | gene | 2 | 2 |
| tlr-4 | gene | — | — |
| trl4 | gene | — | — |