folate drug

Aliases

folic acid, vitamin B9

External links

DrugBank · PubChem

Related entities (7)

Mentioned in (92)

Papers in which this entity is mentioned.

• Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. (2025)
• Evidence and Perspectives for Choline Supplementation during Parenteral Nutrition-A Narrative Review. (2024)
• Early moderate prenatal alcohol exposure and maternal diet impact offspring DNA methylation across species. (2024)
• Choline-An Underappreciated Component of a Mother-to-Be's Diet. (2024)
• A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice. (2024)
• Alcohol blunts pregnancy-mediated insulin resistance and reduces fetal brain glucose despite elevated fetal gluconeogenesis, and these changes associate with fetal weight outcomes. (2023)
• Epigenetics in Alzheimer's Disease. (2022)
• Untargeted Metabolome Analysis Reveals Reductions in Maternal Hepatic Glucose and Amino Acid Content That Correlate with Fetal Organ Weights in a Mouse Model of Fetal Alcohol Spectrum Disorders. (2022)
• The impact of micronutrient supplementation in alcohol-exposed pregnancies on reaction time responses of preschoolers in Ukraine. (2022)
• Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies. (2022)
• Beneficial Effects of Betaine: A Comprehensive Review. (2021)
• Prenatal choline supplementation during mouse pregnancy has differential effects in alcohol-exposed fetal organs. (2021)
• Integrated analysis of multimodal single-cell data. (2021)
• Multifactorial Genetic and Environmental Hedgehog Pathway Disruption Sensitizes Embryos to Alcohol-Induced Craniofacial Defects. (2020)
• Association of Prenatal Alcohol Exposure With Psychological, Behavioral, and Neurodevelopmental Outcomes in Children From the Adolescent Brain Cognitive Development Study. (2020)
• Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview. (2020)
• Modification of stem cell states by alcohol and acetaldehyde. (2020)
• Prenatal Developmental Origins of Future Psychopathology: Mechanisms and Pathways. (2019)
• Prenatal Stress and Maternal Immune Dysregulation in Autism Spectrum Disorders: Potential Points for Intervention. (2019)
• Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE. (2018)
• Implications of altered maternal cytokine concentrations on infant outcomes in children with prenatal alcohol exposure. (2018)
• Prenatal Alcohol Exposure: Profiling Developmental DNA Methylation Patterns in Central and Peripheral Tissues. (2018)
• Immune Dysfunction and Autoimmunity as Pathological Mechanisms in Autism Spectrum Disorders. (2018)
• PDGFRA gene, maternal binge drinking and obstructive heart defects. (2018)
• Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. (2018)
• One-Carbon Metabolism in Health and Disease. (2017)
• Environmental factors influencing the risk of autism. (2017)
• Usual Choline Intakes Are Associated with Egg and Protein Food Consumption in the United States. (2017)
• Dietary choline levels modify the effects of prenatal alcohol exposure in rats. (2017)
• Maternal nutritional status as a contributing factor for the risk of fetal alcohol spectrum disorders. (2016)
• Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis. (2016)
• Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR(mt). (2016)
• The Placenta as a Mediator of Stress Effects on Neurodevelopmental Reprogramming. (2016)
• The impact of micronutrient supplementation in alcohol-exposed pregnancies on information processing skills in Ukrainian infants. (2015)
• Formate metabolism in fetal and neonatal sheep. (2015)
• Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement. (2015)
• Maternal periconceptional alcohol consumption and congenital heart defects. (2015)
• Obstructive heart defects associated with candidate genes, maternal obesity, and folic acid supplementation. (2015)
• A comprehensive view of the epigenetic landscape part I: DNA methylation, passive and active DNA demethylation pathways and histone variants. (2015)
• Inappropriate feeding behaviors and dietary intakes in children with fetal alcohol spectrum disorder or probable prenatal alcohol exposure. (2014)
• Dietary intake, nutrition, and fetal alcohol spectrum disorders in the Western Cape Province of South Africa. (2014)
• Maternal obesity and tobacco use modify the impact of genetic variants on the occurrence of conotruncal heart defects. (2014)
• Conotruncal heart defects and common variants in maternal and fetal genes in folate, homocysteine, and transsulfuration pathways. (2014)
• Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: a model for fetal alcohol spectrum disorders. (2014)
• Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms. (2014)
• Alcohol modulates expression of DNA methyltranferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts. (2013)
• Prenatal alcohol exposure and offspring cognition and school performance. A 'Mendelian randomization' natural experiment. (2013)
• Neurodevelopmental alcohol exposure elicits long-term changes to gene expression that alter distinct molecular pathways dependent on timing of exposure. (2013)
• Alcohol metabolism and epigenetics changes. (2013)
• Inadequate intake of nutrients essential for neurodevelopment in children with fetal alcohol spectrum disorders (FASD). (2013)
• Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: prevention with folic acid. (2013)
• In utero alcohol exposure, epigenetic changes, and their consequences. (2013)
• Nutrition in pregnancy: the argument for including a source of choline. (2013)
• Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
• Associations between multivitamin supplement use and alcohol consumption before pregnancy: Pregnancy Risk Assessment Monitoring System, 2004 to 2008. (2013)
• The role of nutrition in children's neurocognitive development, from pregnancy through childhood. (2013)
• DNA methylation program in developing hippocampus and its alteration by alcohol. (2013)
• Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. (2013)
• Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study. (2013)
• Prenatal maternal depression symptoms and nutrition, and child cognitive function. (2013)
• Choline intake during pregnancy and child cognition at age 7 years. (2013)
• Epigenetic medicine and fetal alcohol spectrum disorders. (2013)
• 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy. (2012)
• Associations between maternal genotypes and metabolites implicated in congenital heart defects. (2012)
• Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. (2012)
• Maternal intake of methyl-donor nutrients and child cognition at 3 years of age. (2012)
• Maternal nutritional status, C(1) metabolism and offspring DNA methylation: a review of current evidence in human subjects. (2012)
• Alcohol alters DNA methylation patterns and inhibits neural stem cell differentiation. (2011)
• What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. (2011)
• Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. (2011)
• Focus on: epigenetics and fetal alcohol spectrum disorders. (2011)
• Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging. (2011)
• Callosal atrophy in mild cognitive impairment and Alzheimer's disease: different effects in different stages. (2010)
• Fetal alcohol spectrum disorders: from research to policy. (2010)
• Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development. (2010)
• Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. (2010)
• Maternal folate-related gene environment interactions and congenital heart defects. (2010)
• The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. (2010)
• Developmental origins of health and disease: environmental exposures. (2009)
• Choline: an essential nutrient for public health. (2009)
• Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation. (2009)
• Impact of maternal stress, depression and anxiety on fetal neurobehavioral development. (2009)
• The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus). (2008)
• Effect of in utero and early-life conditions on adult health and disease. (2008)
• Genetic and environmental factors in complex neurodevelopmental disorders. (2007)
• DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. (2007)
• Choline: critical role during fetal development and dietary requirements in adults. (2006)
• Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. (2006)
• Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. (2005)
• The association of time in the US and diet during pregnancy in low-income women of Mexican descent. (2005)
• The nutrient intakes of mothers of low birth weight babies - a comparison of ethnic groups in East London, UK. (2005)
• Transposable elements: targets for early nutritional effects on epigenetic gene regulation. (2003)

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