AKT1 gene
Evidence from:
primary |
all sources
Related entities (5)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| AKT1 | regulates | GSK3B | — | 1 |
| AKT1 | associated_with | schizophrenia | 0.05 | 1 |
| AKT1 | risk_factor_for | schizophrenia | — | 2 |
| PI3K | interacts_with | AKT1 | — | 1 |
| rs1076560 | interacts_with | AKT1 | — | 1 |
Mentioned in (70)
Papers in which this entity is mentioned.
- Nanopore-based cell-free DNA fragmentation and methylation profiles from the cerebral spinal fluid of patients with lung cancer brain metastases. (2025)
- Extrachromosomal DNA-Driven Oncogene Spatial Heterogeneity and Evolution in Glioblastoma. (2025)
- mutations, genetic mosaicism and human disease. (2022)
- Macrophage Polarization States in the Tumor Microenvironment. (2021)
- Prenatal drug exposure and neurodevelopmental programming of glucocorticoid signalling. (2020)
- TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
- ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing. (2020)
- Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. (2019)
- Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
- The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment. (2019)
- Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study. (2019)
- Genome-Informed Targeted Therapy for Osteosarcoma. (2019)
- The Cancer Spliceome: Reprograming of Alternative Splicing in Cancer. (2018)
- mTORC2 in the dorsomedial striatum of mice contributes to alcohol-dependent F-Actin polymerization, structural modifications, and consumption. (2018)
- Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions. (2018)
- OncoKB: A Precision Oncology Knowledge Base. (2017)
- Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma. (2017)
- Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice. (2017)
- Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors. (2017)
- Interaction of glycosphingolipids GD3 and GD2 with growth factor receptors maintains breast cancer stem cell phenotype. (2017)
- New insights into the generation and role of de novo mutations in health and disease. (2016)
- H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus. (2016)
- Fragment Length of Circulating Tumor DNA. (2016)
- Alcohol Use During Pregnancy is Associated with Specific Alterations in MicroRNA Levels in Maternal Serum. (2016)
- Development and clinical application of an integrative genomic approach to personalized cancer therapy. (2016)
- Truncating Erythropoietin Receptor Rearrangements in Acute Lymphoblastic Leukemia. (2016)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. (2016)
- Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors. (2015)
- Recent genetic findings in schizophrenia and their therapeutic relevance. (2015)
- The cell cycle regulator CCDC6 is a key target of RNA-binding protein EWS. (2015)
- Recurrent somatic mutations in regulatory regions of human cancer genomes. (2015)
- Integrative clinical genomics of advanced prostate cancer. (2015)
- ERBB4 polymorphism and family history of psychiatric disorders on age-related cortical changes in healthy children. (2015)
- Evaluating historical candidate genes for schizophrenia. (2015)
- Regulation of mTORC1 by PI3K signaling. (2015)
- Dissecting FASD through the global transcriptome. (2015)
- The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction. (2014)
- Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies. (2014)
- The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease. (2014)
- Gene-ethanol interactions underlying fetal alcohol spectrum disorders. (2014)
- MiR-153 targets the nuclear factor-1 family and protects against teratogenic effects of ethanol exposure in fetal neural stem cells. (2014)
- Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice. (2013)
- A critical role for PDGFRα signaling in medial nasal process development. (2013)
- Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. (2013)
- Commonality in Down and fetal alcohol syndromes. (2013)
- Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. (2013)
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. (2011)
- DISC1 at 10: connecting psychiatric genetics and neuroscience. (2011)
- Teratogenic effects of thalidomide: molecular mechanisms. (2011)
- Alteration of gene expression by alcohol exposure at early neurulation. (2011)
- Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes. (2010)
- Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3beta phosphorylation. (2010)
- MicroRNAs: master regulators of ethanol abuse and toxicity? (2010)
- rSW-seq: algorithm for detection of copy number alterations in deep sequencing data. (2010)
- Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
- Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction. (2010)
- Sexual dimorphism in the white matter of rodents. (2009)
- Sonic hedgehog ligand partners with caveolin-1 for intracellular transport. (2009)
- Effects of ethanol and ipsapirone on the expression of genes encoding anti-apoptotic proteins and an antioxidant enzyme in ethanol-treated neurons. (2009)
- Modeling the impact of alcohol on cortical development in a dish: strategies from mapping neural stem cell fate. (2008)
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia. (2008)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. (2003)
- Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. (2003)
- Nicotine inhibits palatal fusion and modulates nicotinic receptors and the PI-3 kinase pathway in medial edge epithelia. (2003)
- Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. (2002)
- Pituitary adenylate cyclase-activating polypeptide protects rat cerebellar granule neurons against ethanol-induced apoptotic cell death. (2002)
- Insulin-like growth factor-I overexpression attenuates cerebellar apoptosis by altering the expression of Bcl family proteins in a developmentally specific manner. (2001)
- Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. (1995)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| akt1 | gene | 70 | 194 |
| phospho-akt ser473 | gene | — | — |