LOH phenotype

Aliases

age-associated LOH, loss of heterozygosity

Related entities (1)

Mentioned in (44)

Papers in which this entity is mentioned.

• Whole genome sequencing approach to assess homologous recombination deficiency in a pan-cancer cohort. (2026)
• Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma. (2023)
• Deterministic evolution and stringent selection during preneoplasia. (2023)
• Single-cell genomic variation induced by mutational processes in cancer. (2022)
• Prospective pan-cancer germline testing using MSK-IMPACT informs clinical translation in 751 patients with pediatric solid tumors. (2021)
• Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data. (2021)
• Integrative reconstruction of cancer genome karyotypes using InfoGenomeR. (2021)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes. (2021)
• Immuno-genomic landscape of osteosarcoma. (2020)
• Accucopy: Accurate and Fast Inference of Allele-specific Copy Number Alterations from Low-coverage Low-purity Tumor Sequencing Data (2020)
• Ploidy- and Purity-Adjusted Allele-Specific DNA Analysis Using CLONETv2. (2019)
• Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy. (2019)
• The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment. (2019)
• VCF2CNA: A tool for efficiently detecting copy-number alterations in VCF genotype data and tumor purity. (2019)
• Best practices for bioinformatic characterization of neoantigens for clinical utility. (2019)
• Pan-cancer whole-genome analyses of metastatic solid tumours. (2019)
• Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours. (2018)
• Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer. (2018)
• The Immune Landscape of Cancer. (2018)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
• Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. (2018)
• Patient-derived xenografts undergo mouse-specific tumor evolution. (2017)
• Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. (2017)
• ReMixT: clone-specific genomic structure estimation in cancer. (2017)
• Copy-number signatures and mutational processes in ovarian carcinoma (2017)
• Sequenza: allele-specific copy number and mutation profiles from tumor sequencing data. (2015)
• MBASED: allele-specific expression detection in cancer tissues and cell lines. (2014)
• Hidden Markov Model-Based CNV Detection Algorithms for Illumina Genotyping Microarrays. (2014)
• Break-induced replication is a source of mutation clusters underlying kataegis. (2014)
• Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. (2014)
• TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data. (2014)
• PyClone: statistical inference of clonal population structure in cancer. (2014)
• THetA: inferring intra-tumor heterogeneity from high-throughput DNA sequencing data. (2013)
• A comparative analysis of algorithms for somatic SNV detection in cancer. (2013)
• Absolute quantification of somatic DNA alterations in human cancer. (2012)
• Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. (2012)
• Control-FREEC: a tool for assessing copy number and allelic content using next-generation sequencing data. (2012)
• Detectable clonal mosaicism from birth to old age and its relationship to cancer. (2012)
• VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing. (2012)
• Massive genomic rearrangement acquired in a single catastrophic event during cancer development. (2011)
• BRCA1 and BRCA2: different roles in a common pathway of genome protection. (2011)
• Allele-specific copy number analysis of tumors. (2010)
• TumorBoost: normalization of allele-specific tumor copy numbers from a single pair of tumor-normal genotyping microarrays. (2010)
• Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. (2009)

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