Aβ accumulation phenotype

Aliases: amyloid beta accumulation, amyloid beta deposition, amyloid-beta accumulation, beta-amyloid deposition

Evidence from: primary | all sources

Related entities (12)

Subject	Relation	Object	p-value	Evidence
ACE	protective_against	Aβ accumulation	—	1
Amyloid-beta	protective_against	Aβ accumulation	—	1
APP	regulates	Aβ accumulation	—	1
Aβ accumulation	regulates	p-tau	—	1
Aβ accumulation	risk_factor_for	tauopathy	—	1
caloric restriction	protective_against	Aβ accumulation	—	1
environmental enrichment	protective_against	Aβ accumulation	—	1
exercise	protective_against	Aβ accumulation	—	1
pulse wave velocity	associated_with	Aβ accumulation	—	1
wine	protective_against	Aβ accumulation	—	1
β-secretase inhibitor	protective_against	Aβ accumulation	—	1
γ-secretase inhibitor	protective_against	Aβ accumulation	—	1

Mentioned in (10)

Papers in which this entity is mentioned.

A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. (2020)
Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice. (2016)
New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. (2014)
Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice. (2013)
Transgenic mouse models of Alzheimer's disease. (2010)
Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. (2009)

Merged raw entities (6)

All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.

Raw name	Type	Papers	Mentions
aβ accumulation	phenotype	6	7
aβ deposition	phenotype	5	10
amyloid beta accumulation	phenotype	1	1
amyloid-beta accumulation	phenotype	—	—
amyloid beta deposition	phenotype	—	—
beta-amyloid deposition	phenotype	—	—