Phosphatidylcholine drug

External links

DrugBank · PubChem

Related entities (1)

Mentioned in (53)

Papers in which this entity is mentioned.

• Safe start, a hybrid intervention to reduce alcohol exposed pregnancies: protocol for a randomized controlled trial. (2026)
• Alcohol Exposure May Increase Prenatal Choline Needs Through Redirection of Choline into Lipid Synthesis Rather than Methyl Donation. (2025)
• Evidence and Perspectives for Choline Supplementation during Parenteral Nutrition-A Narrative Review. (2024)
• Choline-An Underappreciated Component of a Mother-to-Be's Diet. (2024)
• A Narrative Review on Maternal Choline Intake and Liver Function of the Fetus and the Infant; Implications for Research, Policy, and Practice. (2024)
• Untargeted and Targeted Blood Lipidomic Signature Profile of Gestational Alcohol Exposure. (2023)
• The effects of gestational choline supplementation on cerebellar Purkinje cell number in the sheep model of binge alcohol exposure during the first trimester-equivalent. (2022)
• Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies. (2022)
• Beneficial Effects of Betaine: A Comprehensive Review. (2021)
• Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis. (2021)
• Maternal choline supplementation mitigates alcohol exposure effects on neonatal brain volumes. (2021)
• Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. (2021)
• Choline metabolome response to prenatal choline supplementation across pregnancy: A randomized controlled trial. (2021)
• Choline, Neurological Development and Brain Function: A Systematic Review Focusing on the First 1000 Days. (2020)
• Four-year follow-up of a randomized controlled trial of choline for neurodevelopment in fetal alcohol spectrum disorder. (2020)
• Maternal choline supplementation mitigates alcohol-induced fetal cranio-facial abnormalities detected using an ultrasonographic examination in a sheep model. (2019)
• Elimination Characteristics of the Alcohol Biomarker Phosphatidylethanol (PEth) in Blood during Alcohol Detoxification. (2019)
• Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. (2018)
• Alcohol and Mortality: Combining Self-Reported (AUDIT-C) and Biomarker Detected (PEth) Alcohol Measures Among HIV Infected and Uninfected. (2018)
• One-Carbon Metabolism in Health and Disease. (2017)
• Maternal choline supplementation during murine pregnancy modulates placental markers of inflammation, apoptosis and vascularization in a fetal sex-dependent manner. (2017)
• Choline and Working Memory Training Improve Cognitive Deficits Caused by Prenatal Exposure to Ethanol. (2017)
• Usual Choline Intakes Are Associated with Egg and Protein Food Consumption in the United States. (2017)
• Maternal choline supplementation in a sheep model of first trimester binge alcohol fails to protect against brain volume reductions in peripubertal lambs. (2016)
• The Formation, Elimination, Interpretation, and Future Research Needs of Phosphatidylethanol for Research Studies and Clinical Practice. (2016)
• Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis. (2016)
• Adolescent Choline Supplementation Attenuates Working Memory Deficits in Rats Exposed to Alcohol During the Third Trimester Equivalent. (2016)
• Supplemental choline does not attenuate the effects of neonatal ethanol administration on habituation of the heart rate orienting response in rats. (2014)
• Development of thalamocortical connectivity during infancy and its cognitive correlations. (2014)
• Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule. (2014)
• Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in β-endorphin-producing POMC neurons of the hypothalamus. (2013)
• Nutrition in pregnancy: the argument for including a source of choline. (2013)
• Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. (2013)
• Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. (2013)
• Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study. (2013)
• Neuroprotective actions of perinatal choline nutrition. (2013)
• Choline supplementation mitigates trace, but not delay, eyeblink conditioning deficits in rats exposed to alcohol during development. (2012)
• Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. (2012)
• Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. (2012)
• Maternal nutritional status, C(1) metabolism and offspring DNA methylation: a review of current evidence in human subjects. (2012)
• What choline metabolism can tell us about the underlying mechanisms of fetal alcohol spectrum disorders. (2011)
• Focus on: magnetic resonance-based studies of fetal alcohol spectrum disorders in animal models. (2011)
• Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development. (2010)
• Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. (2010)
• Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. (2009)
• Genome-wide identification of Saccharomyces cerevisiae genes required for maximal tolerance to ethanol. (2009)
• Choline: an essential nutrient for public health. (2009)
• Magnetic resonance spectroscopy outcomes from a comprehensive magnetic resonance study of children with fetal alcohol spectrum disorders. (2009)
• Protein kinases and addiction. (2008)
• Choline supplementation attenuates learning deficits associated with neonatal alcohol exposure in the rat: effects of varying the timing of choline administration. (2008)
• Choline: critical role during fetal development and dietary requirements in adults. (2006)
• Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. (2005)
• Modeling alcohol's effects on organs in animal models. (2000)

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