H3K27ac drug
Evidence from:
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all sources
Related entities (14)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| enhancer | associated_with | H3K27ac | — | 1 |
| H3K27ac | expressed_in | angular gyrus | — | 1 |
| H3K27ac | expressed_in | cingulate cortex | — | 1 |
| H3K27ac | expressed_in | dorsolateral prefrontal cortex | — | 1 |
| H3K27ac | associated_with | ENCODE project | — | 1 |
| H3K27ac | associated_with | enhancer | — | 1 |
| H3K27ac | interacts_with | enhancer | — | 1 |
| H3K27ac | associated_with | HeLa | — | 1 |
| H3K27ac | associated_with | PAU | — | 1 |
| H3K27ac | associated_with | Roadmap Epigenomics | — | 1 |
| H3K27ac | expressed_in | substantia nigra | — | 1 |
| H3K27me3 | associated_with | H3K27ac | — | 1 |
| Roadmap Epigenomics consortium | associated_with | H3K27ac | — | 1 |
| rs1409568 | interacts_with | H3K27ac | — | 1 |
Mentioned in (55)
Papers in which this entity is mentioned.
- Advancing regulatory variant effect prediction with AlphaGenome. (2026)
- Enhancer activation from transposable elements in extrachromosomal DNA. (2025)
- Three-dimensional genome landscape of primary human cancers. (2025)
- Nucleotide Transformer: building and evaluating robust foundation models for human genomics. (2025)
- Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
- Global impact of unproductive splicing on human gene expression. (2024)
- Machine-guided design of cell-type-targeting cis-regulatory elements. (2024)
- Transient loss of Polycomb components induces an epigenetic cancer fate. (2024)
- A DNA methylation atlas of normal human cell types. (2023)
- Towards understandings of serine/arginine-rich splicing factors. (2023)
- DNA methylation and general psychopathology in childhood: an epigenome-wide meta-analysis from the PACE consortium. (2023)
- Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. (2022)
- At the dawn: cell-free DNA fragmentomics and gene regulation. (2022)
- GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate. (2022)
- Massively parallel reporter perturbation assays uncover temporal regulatory architecture during neural differentiation. (2022)
- Simultaneous epigenetic perturbation and genome imaging reveal distinct roles of H3K9me3 in chromatin architecture and transcription. (2020)
- Discovery of regulatory noncoding variants in individual cancer genomes by using cis-X. (2020)
- Structural variation in the sequencing era. (2020)
- Folding Keratin Gene Clusters during Skin Regional Specification. (2020)
- Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers. (2020)
- Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits. (2020)
- Super-enhancers: critical roles and therapeutic targets in hematologic malignancies. (2019)
- Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes. (2019)
- Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure. (2019)
- Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. (2019)
- Alcohol metabolism contributes to brain histone acetylation. (2019)
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. (2018)
- The Gene Encoding Protocadherin 9 (PCDH9), a Novel Risk Factor for Major Depressive Disorder. (2018)
- Ventral striatal regulation of CREM mediates impulsive action and drug addiction vulnerability. (2018)
- Genome-wide association study identifies a novel locus for cannabis dependence. (2018)
- Positively selected enhancer elements endow osteosarcoma cells with metastatic competence. (2018)
- The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions. (2018)
- EWS/FLI Confers Tumor Cell Synthetic Lethality to CDK12 Inhibition in Ewing Sarcoma. (2018)
- Nanopore Sequencing Reveals High-Resolution Structural Variation in the Cancer Genome (2017)
- Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments. (2017)
- Orthotopic patient-derived xenografts of paediatric solid tumours. (2017)
- Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain. (2017)
- DNA replication timing during development anticipates transcriptional programs and parallels enhancer activation. (2017)
- Dysregulation of Cortical Neuron DNA Methylation Profile in Autism Spectrum Disorder. (2017)
- PGBD5 promotes site-specific oncogenic mutations in human tumors. (2017)
- Novel genetic loci underlying human intracranial volume identified through genome-wide association. (2016)
- Nuclear organization and 3D chromatin architecture in cognition and neuropsychiatric disorders. (2016)
- Satb2 determines miRNA expression and long-term memory in the adult central nervous system. (2016)
- Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
- Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. (2016)
- The PsychENCODE project. (2015)
- Epigenomics and the structure of the living genome. (2015)
- WASP: allele-specific software for robust molecular quantitative trait locus discovery. (2015)
- An atlas of active enhancers across human cell types and tissues. (2014)
- EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcoma. (2014)
- Diminishing return for increased Mappability with longer sequencing reads: implications of the k-mer distributions in the human genome. (2014)
- Global epigenomic reconfiguration during mammalian brain development. (2013)
- DNA methylation contributes to natural human variation. (2013)
- Landscape of transcription in human cells. (2012)
- An integrated encyclopedia of DNA elements in the human genome. (2012)
Merged raw entities (2)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| h3k27ac | drug | 54 | 208 |
| h3k27 acetylation | drug | 3 | 3 |