genomic instability phenotype

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Mentioned in (45)

Papers in which this entity is mentioned.

• Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models. (2026)
• Whole-genome landscapes of 1,364 breast cancers. (2026)
• Enhancer activation from transposable elements in extrachromosomal DNA. (2025)
• FET fusion oncoproteins disrupt physiologic DNA repair and create a targetable opportunity for ATR inhibitor therapy. (2025)
• Transcription start sites experience a high influx of heritable variants fueled by early development. (2025)
• Combination of genomic instability score and TP53 status for prognosis prediction in lung adenocarcinoma. (2023)
• Gene-alcohol interactions in birth defects. (2023)
• Deterministic evolution and stringent selection during preneoplasia. (2023)
• Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers. (2023)
• Single-cell genomic variation induced by mutational processes in cancer. (2022)
• Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers. (2022)
• Application of third-generation sequencing in cancer research. (2021)
• Modification of stem cell states by alcohol and acetaldehyde. (2020)
• The Network of Cancer Genes (NCG): a comprehensive catalogue of known and candidate cancer genes from cancer sequencing screens. (2019)
• Association of BRCA1- and BRCA2-deficiency with mutation burden, expression of PD-L1/PD-1, immune infiltrates, and T cell-inflamed signature in breast cancer. (2019)
• Comprehensive analysis of structural variants in breast cancer genomes using single molecule sequencing (2019)
• Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells. (2018)
• Genome doubling shapes the evolution and prognosis of advanced cancers. (2018)
• The Immune Landscape of Cancer. (2018)
• Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes (2018)
• Patterns and mechanisms of structural variations in human cancer. (2018)
• Copy number signatures and mutational processes in ovarian carcinoma. (2018)
• Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden. (2017)
• Patient-derived xenografts undergo mouse-specific tumor evolution. (2017)
• Copy-number signatures and mutational processes in ovarian carcinoma (2017)
• New insights into the generation and role of de novo mutations in health and disease. (2016)
• A role for human homologous recombination factors in suppressing microhomology-mediated end joining. (2016)
• Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors. (2016)
• A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. (2015)
• A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. (2014)
• Recurrent somatic structural variations contribute to tumorigenesis in pediatric osteosarcoma. (2014)
• Involvement of p53 in the repair of DNA double strand breaks: multifaceted Roles of p53 in homologous recombination repair (HRR) and non-homologous end joining (NHEJ). (2014)
• RNA splicing: a new player in the DNA damage response. (2013)
• Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner. (2012)
• Microsatellites with macro-influence in ewing sarcoma. (2012)
• BRCA1 and BRCA2: different roles in a common pathway of genome protection. (2011)
• Regulation of chromatin by histone modifications. (2011)
• Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. (2011)
• Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. (2011)
• Integrative analysis of the melanoma transcriptome. (2010)
• Cellular metabolic stress: considering how cells respond to nutrient excess. (2010)
• Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. (2009)
• 3' end mRNA processing: molecular mechanisms and implications for health and disease. (2008)
• MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. (2008)
• Genomic disorders: molecular mechanisms for rearrangements and conveyed phenotypes. (2005)

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