NKX2-1 gene
Evidence from:
primary |
all sources
Related entities (27)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Alexa Fluor 488 | interacts_with | NKX2-1 | — | 1 |
| Ascl1 | interacts_with | NKX2-1 | — | 1 |
| Dlx1 | interacts_with | NKX2-1 | — | 1 |
| Dlx2 | interacts_with | NKX2-1 | — | 1 |
| FOXG1 | associated_with | NKX2-1 | — | 1 |
| interneuron | regulates | NKX2-1 | — | 1 |
| medial ganglionic eminence | regulates | NKX2-1 | — | 1 |
| NKX2-1 | regulates | cortex | — | 1 |
| NKX2-1 | expressed_in | GABA | — | 1 |
| NKX2-1 | expressed_in | globus pallidus | — | 1 |
| NKX2-1 | expressed_in | intermediate progenitors | — | 1 |
| NKX2-1 | expressed_in | interneuron | — | 1 |
| NKX2-1 | expressed_in | LGE | — | 1 |
| NKX2-1 | regulates | Lhx6 | — | 1 |
| NKX2-1 | regulates | Lhx8 | — | 1 |
| NKX2-1 | expressed_in | medial ganglionic eminence | — | 3 |
| NKX2-1 | expressed_in | MZ | — | 1 |
| NKX2-1 | associated_with | Sox6 | — | 1 |
| NKX2-1 | expressed_in | striatal interneurons | — | 1 |
| NKX2-1 | expressed_in | striatum | — | 1 |
| NKX2-1 | associated_with | striatum | — | 1 |
| NKX2-1 | regulates | striatum | — | 1 |
| NKX2-1 | expressed_in | SVZ | — | 1 |
| NKX2-1 | expressed_in | ventricular zone | — | 1 |
| NKX2-1 | expressed_in | VZ | — | 1 |
| Shh | regulates | NKX2-1 | — | 1 |
| ZEB2 | regulates | NKX2-1 | — | 1 |
Mentioned in (39)
Papers in which this entity is mentioned.
- Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling. (2022)
- Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing. (2022)
- Inferring gene expression from cell-free DNA fragmentation profiles. (2022)
- Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription. (2021)
- Prenatal Environment That Affects Neuronal Migration. (2019)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome. (2018)
- Assembly of functionally integrated human forebrain spheroids. (2017)
- Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors. (2017)
- Ethanol itself is a holoprosencephaly-inducing teratogen. (2017)
- Single-Cell Profiling of an In Vitro Model of Human Interneuron Development Reveals Temporal Dynamics of Cell Type Production and Maturation. (2017)
- Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. (2013)
- The sox family of transcription factors: versatile regulators of stem and progenitor cell fate. (2013)
- A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. (2013)
- Rescue of holoprosencephaly in fetal alcohol-exposed Cdon mutant mice by reduced gene dosage of Ptch1. (2013)
- Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. (2013)
- SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. (2012)
- Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice. (2012)
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers. (2011)
- Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice. (2011)
- MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. (2011)
- Molecular mechanisms of long noncoding RNAs. (2011)
- Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates. (2010)
- Pathogenesis of holoprosencephaly. (2009)
- Evolution of the neocortex: a perspective from developmental biology. (2009)
- The embryonic preoptic area is a novel source of cortical GABAergic interneurons. (2009)
- Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly. (2008)
- Ethanol consumption during early pregnancy alters the disposition of tangentially migrating GABAergic interneurons in the fetal cortex. (2008)
- The requirement of Nkx2-1 in the temporal specification of cortical interneuron subtypes. (2008)
- Molecular specification and patterning of progenitor cells in the lateral and medial ganglionic eminences. (2008)
- Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. (2007)
- Transcriptional regulation of cortical interneuron development. (2007)
- Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. (2007)
- The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes. (2007)
- Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage. (2006)
- Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. (2005)
- Temporal perturbations in sonic hedgehog signaling elicit the spectrum of holoprosencephaly phenotypes. (2004)
- Origins of cortical interneuron subtypes. (2004)
- Layer specification of transplanted interneurons in developing mouse neocortex. (2003)
Merged raw entities (4)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| nkx2-1 | gene | 30 | 237 |
| nkx2.1 | gene | 27 | 147 |
| ttf-1 | gene | 2 | 3 |
| nkx2–1 | gene | — | — |