amyloid plaques phenotype
Evidence from:
primary |
all sources
Related entities (7)
| Subject | Relation | Object | p-value | Evidence |
|---|---|---|---|---|
| Alzheimer's disease | biomarker_for | amyloid plaques | — | 1 |
| Alzheimer’s disease | associated_with | amyloid plaques | — | 1 |
| Amyloid-beta peptide | associated_with | amyloid plaques | — | 1 |
| amyloid plaques | associated_with | Alzheimer's disease | — | 2 |
| amyloid plaques | biomarker_for | Alzheimer's disease | — | 1 |
| apoE | associated_with | amyloid plaques | — | 1 |
| β-amyloid | associated_with | amyloid plaques | — | 1 |
Mentioned in (18)
Papers in which this entity is mentioned.
- Human 3D brain organoids: steering the demolecularization of brain and neurological diseases. (2023)
- A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. (2021)
- Interpretation of risk loci from genome-wide association studies of Alzheimer's disease. (2020)
- TGF-β/Smad3 Signalling Modulates GABA Neurotransmission: Implications in Parkinson's Disease. (2020)
- Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. (2018)
- ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease. (2017)
- Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations. (2017)
- Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. (2016)
- Physical exercise-induced adult neurogenesis: a good strategy to prevent cognitive decline in neurodegenerative diseases? (2014)
- Resting-state network disruption and APOE genotype in Alzheimer's disease: a lagged functional connectivity study. (2012)
- The role of DYRK1A in neurodegenerative diseases. (2011)
- Apolipoprotein E: from lipid transport to neurobiology. (2011)
- Transgenic mouse models of Alzheimer's disease. (2010)
- Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. (2010)
- Obesity is linked with lower brain volume in 700 AD and MCI patients. (2010)
- Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. (2009)
- PIASx is a MEF2 SUMO E3 ligase that promotes postsynaptic dendritic morphogenesis. (2007)
- Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain. (2001)
Merged raw entities (3)
All extracted name/type variants the normalize job merged into this entity. Use this to spot wrong merges, or aliases that should be split off.
| Raw name | Type | Papers | Mentions |
|---|---|---|---|
| amyloid plaques | phenotype | 16 | 21 |
| aβ plaques | phenotype | 3 | 4 |
| extracellular amyloid plaques | phenotype | — | — |