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gabapentin protective_against alcohol dependence

Subject
gabapentin
Relation
protective_against
Object
alcohol dependence
p-value
Evidence from: primary | all sources

Evidence (3 sources)

Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015) PMID:25516156 primary
clinical trial showing the potential of repurposing gabapentin ... for treating AD
confidence: 0.95
Gabapentin treatment for alcohol dependence: a randomized clinical trial. (2014) PMID:24190578 cited
gabapentin (particularly the 1800 mg dose) effectively treated alcohol dependence
confidence: 0.96
Gabapentin treatment for alcohol dependence: a randomized clinical trial. (2014) PMID:24190578 cited
pre‑clinical rationale for evaluating gabapentin as a treatment for alcohol dependence
confidence: 0.80