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major depressive disorder associated_with prefrontal cortex

Subject
major depressive disorder
Relation
associated_with
Object
prefrontal cortex
p-value
Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. (2018) PMID:29700475 cited
The genetic results best match gene expression patterns in prefrontal ... anatomical regions that show differences between MDD cases and controls.
confidence: 0.95
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. (2018) PMID:29700475 cited
Only brain samples showed significant enrichment ... Prefrontal cortex ... were implicated in a large meta-analysis of brain MRI findings in adult MDD cases.
confidence: 0.96