naltrexone protective_against alcoholism

Subject: naltrexone
Relation: protective_against
Object: alcoholism
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. (2015) PMID:25516156 primary

three FDA‑approved drugs for AD (disulfiram, naltrexone, and acamprosate)

confidence: 0.80

The genetics of the opioid system and specific drug addictions. (2012) PMID:22547174 cited

Two antagonists of opioid receptors are used for the treatment for AD.

confidence: 0.70