HDL cholesterol regulates LDLR

Subject: HDL cholesterol
Relation: regulates
Object: LDLR
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression. (2021) PMID:34475573 cited

higher blood HDL levels can result in stronger reverse cholesterol transport via HDL ... which may result in downregulation of LDLR

confidence: 0.85