Sox2 expressed_in NPCs
Evidence from:
primary |
all sources
Evidence (2 sources)
Early pathogenic event of Alzheimer's disease documented in iPSCs from patients with PSEN1 mutations.
(2017)
PMID:27926491
cited
more than 90% of the cells expressed NPC markers (Nestin and SOX2)
confidence: 0.97
Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
(2016)
PMID:27622770
cited
SOX2-positive neural progenitor cells ... immunoreactivity for SOX2 appeared to decrease
confidence: 0.95