calcineurin associated_with addiction
Evidence from:
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Evidence (3 sources)
Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease.
(2010)
PMID:20590401
cited
The evidence is consistent with modest, polygenic contributions from variants at the PPP3CA locus in addiction.
confidence: 0.88
Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease.
(2010)
PMID:20590401
cited
support roles for PPP3CA ... in addiction
confidence: 0.95
Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease.
(2010)
PMID:20590401
cited
PPP3CA is thus a strong candidate to play central roles in addiction ...
confidence: 0.95