polygenic risk score biomarker_for type 2 diabetes
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Evidence (3 sources)
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.
(2022)
PMID:35765100
cited
predictive performance of the PRS was only assessed for prevalent T2D cases
confidence: 0.90
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.
(2022)
PMID:35765100
cited
We next evaluated the trans-ancestry PRS ... T2D cases were defined with ... glucose or use of any glucose-lowering medications.
confidence: 0.90
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.
(2022)
PMID:35765100
cited
at the top 2% of the PRS distribution, an approximately three-fold increase in T2D risk was observed relative to the remaining 98% of the individuals
confidence: 0.95