OPRM1 A118G associated_with European ancestry
Evidence from:
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Evidence (8 sources)
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.
(2017)
PMID:28134463
cited
Findings are mixed for individuals of European ancestry.
confidence: 0.60
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.
(2017)
PMID:28134463
cited
Many studies have examined the A118G SNP and response to NTX in individuals with AUD who are of European ancestry.
confidence: 0.90
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.
(2017)
PMID:28134463
cited
While the findings are mixed for individuals of European ancestry...
confidence: 0.90
An association was observed between the 118G allele and opioid addiction in ... EA ...
confidence: 0.85
The 118G allele was shown to be represented by a specific haplotype ... in EA subjects.
confidence: 0.94
The 118G allele is common in persons of European (15–30%).
confidence: 0.95
Haplotype block structure of the genomic region of the mu opioid receptor gene.
(2011)
PMID:21160491
cited
the lesser prevalence in European Americans may be explained by genetic drift and/or selective advantage.
confidence: 0.88
Haplotype block structure of the genomic region of the mu opioid receptor gene.
(2011)
PMID:21160491
cited
in European Americans, the 118G variant allele is positioned within a specific haplogroup
confidence: 0.85