cortex associated_with schizophrenia
Evidence from:
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Evidence (5 sources)
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
(2021)
PMID:34002096
cited
Findings similar to those reported in GWAS data of schizophrenia, with enrichment in cortex.
confidence: 0.80
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
(2018)
PMID:29632380
cited
nearly every brain region ... was found to be enriched at FDR<5% in schizophrenia (cortex is a brain region)
confidence: 0.90
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
misconstruction of the cortex ... observed in ... schizophrenia
confidence: 0.93
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
maldevelopment of the cortex in schizophrenia iPSC organoids
confidence: 0.88
Cerebral organoids reveal early cortical maldevelopment in schizophrenia-computational anatomy and genomics, role of FGFR1.
(2017)
PMID:30446636
cited
turning off nFGFR1 in the schizophrenia cortical cells disrupts their further development.
confidence: 0.80