OPRM1 associated_with opioid dependence

Evidence from: primary | all sources

Evidence (6 sources)

unequivocal GWS association signal for the intron 1 locus in OPRM1 ... association with OA

confidence: 0.96

GWAS of OUD58 ... have identified GWS associations with OPRM1 variants

confidence: 0.90

association between variants in intron 1 of OPRM1 with OA

confidence: 0.95

we examined the associations of specific OPRM1 haplotypes with OA

confidence: 0.80

MOR ... controls the rewarding effects of many drugs of abuse, including opioids

confidence: 0.89

Additional connections between OPRM1 and treatments for opioid ... addiction are also promising.

confidence: 0.60