nicotine interacts_with CYP2A6
Evidence from:
primary |
all sources
Evidence (1 sources)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
70–80% of nicotine is converted to cotinine, mediated largely by the liver enzyme cytochrome P450 CYP2A6.
confidence: 0.95