Klb interacts_with Fgf21

Subject: Klb
Relation: interacts_with
Object: Fgf21
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117). (2017) PMID:28937693 cited

β-Klotho is a receptor for the liver-expressed hormone FGF21

confidence: 0.95

FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. (2012) PMID:22792234 cited

β-klotho expressing tissue, WAT, was necessary for FGF21 to elicit efficacy

confidence: 0.90