nicotine targets nicotinic acetylcholine receptor
Evidence from:
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Evidence (4 sources)
nicotinic acetylcholine receptors (nAChRs) are the primary target for nicotine
confidence: 0.96
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior.
(2012)
PMID:23040810
cited
addictive effects of nicotine are mediated primarily through stimulation of nAChRs
confidence: 0.96
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
Nicotine and other nicotine agonists will elicit different responses of these receptors depending on the subtype it acts on
confidence: 0.92
Nicotine binds to nicotinic acetylcholine receptors (nAChRs).
confidence: 0.95