rs1360780 risk_factor_for Post-Traumatic Stress Disorder
Evidence from:
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Evidence (4 sources)
Epigenetic mechanisms in alcohol- and adversity-induced developmental origins of neurobehavioral functioning.
(2018)
PMID:29305195
cited
Demethylation of FKBP5 in carriers of the FKBP5 rs1360780 risk allele ... mediated the relationship between childhood abuse and increased PTSD prevalence.
confidence: 0.95
STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.
(2016)
PMID:27038411
cited
Participants were categorized ... based on how many “risk” alleles comprised their genotype ... risk (T) allele.
confidence: 0.85
STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.
(2016)
PMID:27038411
cited
risk alleles for an FKBP5 SNP ... closely associated with PTSD risk
confidence: 0.94
STRUCTURAL AND FUNCTIONAL CONNECTIVITY IN POSTTRAUMATIC STRESS DISORDER: ASSOCIATIONS WITH FKBP5.
(2016)
PMID:27038411
cited
individuals who carried two risk alleles for ... rs1360780 ... and met criteria for a PTSD diagnosis demonstrated relatively poorer cingulum connectivity
confidence: 0.90