genetic variants associated_with outcome
Evidence from:
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Evidence (4 sources)
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.
(2021)
PMID:34446935
primary
genetic variants impact clinical outcomes
confidence: 0.92
Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.
(2017)
PMID:28960498
cited
the same reference allele must be used for associations with each risk factor and with the outcome.
confidence: 0.88
Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.
(2017)
PMID:28960498
cited
associations between the genetic variants ... with the outcome
confidence: 0.90
Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy.
(2017)
PMID:28960498
cited
αj is the direct effect of the genetic variant on the outcome
confidence: 0.90