Klb associated_with alcohol
Evidence from:
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all sources
Evidence (16 sources)
Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder.
(2024)
PMID:39149227
primary
KLB, a gene associated with alcohol consumption
confidence: 0.95
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.
(2022)
PMID:33985350
primary
KLB ... were previously associated with alcohol consumption behaviors
confidence: 0.95
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
Five of the loci were previously associated with a self-reported measure of alcohol consumption: GCKR, KLB, ADH1B, ADH1C, and SLC39A8.
confidence: 0.96
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations.
(2019)
PMID:30940813
primary
KLB was associated with alcohol consumption
confidence: 0.98
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
replicated the association between KLB ... and alcohol consumption
confidence: 0.96
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
robust association of this gene with both alcohol consumption
confidence: 0.90
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
(2019)
PMID:30336701
cited
identified numerous loci ... that influence alcohol consumption, including ... KLB (encoding β-klotho)
confidence: 0.94
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
KLB ... significantly associated with alcohol consumption.
confidence: 0.95
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
a SNP in KLB was associated with alcohol consumption in humans
confidence: 0.94
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
Two hits were identified on chromosome 4p14 in the KLB gene that was previously associated with alcohol consumption.
confidence: 0.94
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
KLB SNPs ... contribute to alcohol consumption
confidence: 0.95
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
identified 4 loci associated with alcohol consumption ... including KLB
confidence: 0.96
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
KLB gene that was previously associated with alcohol consumption in a large GWAS of >105 000 Europeans.
confidence: 0.97
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
The gene encoding β-Klotho (KLB) has recently been associated with alcohol consumption
confidence: 0.90
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117).
(2017)
PMID:28937693
cited
A SNP in KLB was also associated with alcohol consumption
confidence: 0.96
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study.
(2017)
PMID:28485404
cited
the locus near KLB showed the strongest association with alcohol consumption in our meta-analysis
confidence: 0.96