WIN 55,212-2 targets CB1 receptor

Subject: WIN 55,212-2
Relation: targets
Object: CB1 receptor
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

WIN application reliably decreased excitatory neurotransmission in a CB1-dependent manner.

confidence: 0.95

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

exogenous activation of CB1 by WIN (1 μM)

confidence: 0.96

Adolescent chronic mild stress alters hippocampal CB1 receptor-mediated excitatory neurotransmission and plasticity. (2013) PMID:24035826 cited

WIN is a CB1 agonist; CB1 is encoded by the CNR1 gene

confidence: 0.88