rs1051730 associated_with smoking quantity
Evidence from:
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Evidence (4 sources)
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
assuming that it is mediated through the polymorphism's association with smoking quantity
confidence: 0.70
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
any association observed ... between rs1051730 and smoking cessation in pregnancy would be secondary to the known association with smoking quantity
confidence: 0.90
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
Thorgeirsson et al. observed that the same variant was associated with smoking quantity in smokers.
confidence: 0.94
A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy.
(2009)
PMID:19429911
cited
SNP rs1051730 ... was associated with smoking quantity ... Each additional copy ... was associated with an increase of 0.095 smoking quantity units (P = 6 × 10−20).
confidence: 0.99