disulfiram targets ALDH2

Subject: disulfiram
Relation: targets
Object: ALDH2
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Genetic studies of alcohol dependence in the context of the addiction cycle. (2017) PMID:28118990 cited

basis for the use of disulfiram, the first FDA‑approved medication for alcohol dependence

confidence: 0.80

The genetic basis of addictive disorders. (2012) PMID:22640768 cited

Disulfiram blocks aldehyde dehydrogenase (ALDH2).

confidence: 0.90