rs578776 interacts_with rs16969968
Evidence from:
primary |
all sources
Evidence (3 sources)
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
has only low correlation with rs16969968 (r2 < 0.25)
confidence: 0.90
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
rs578776 remains significant after controlling for rs16969968; the second SNP remains significant in EAs
confidence: 0.88
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
(2009)
PMID:19706762
cited
Correlation between rs578776 and rs16969968 is low (r2 = 0.2) with D′ = −1.0, and both SNPs are significant in joint analyses.
confidence: 0.90