rs1051730 associated_with CHRNA5

Subject: rs1051730
Relation: associated_with
Object: CHRNA5
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Genetic variability in the regulation of gene expression in ten regions of the human brain. (2014) PMID:25174004 cited

region of high linkage disequilibrium that covers the related genes CHRNA5 and CHRNB4

confidence: 0.85

TTC12-ANKK1-DRD2 and CHRNA5-CHRNA3-CHRNB4 influence different pathways leading to smoking behavior from adolescence to mid-adulthood. (2011) PMID:21168125 cited

for CHRNA5-CHRNA3-CHRNB4, the most significantly associated allele was rs1051730[A].

confidence: 0.85

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy. (2009) PMID:19429911 cited

rs1051730 SNP in the CHRNA5–CHRNA3–CHRNB4 gene cluster

confidence: 0.95