Chrna3 associated_with smoking behavior
Evidence from:
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Evidence (3 sources)
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
genetic variants ... account for a very small proportion of the variance in smoking behavior (<5%)
confidence: 0.80
Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes.
(2012)
PMID:22290489
cited
association of SNPs in the CHRNA5-CHRNA3-CHRNB4 gene cluster with smoking behavior
confidence: 0.80
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.
(2008)
PMID:18783506
cited
a highly correlated CHRNA5/CHRNA3 haplotype ... was shown to be associated strongly (P < 10−6) with smoking behavior
confidence: 0.95