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ALDH2 interacts_with acetaldehyde

Subject
ALDH2
Relation
interacts_with
Object
acetaldehyde
p-value
Evidence from: primary | all sources

Evidence (6 sources)

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study. (2017) PMID:28485404 cited
processing of ALDH2 ... accumulation of acetaldehyde
confidence: 0.90
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. (2012) PMID:22348705 cited
Acetaldehyde is oxidized to acetate by aldehyde dehydrogenase (ALDH)
confidence: 0.96
The genetic basis of addictive disorders. (2012) PMID:22640768 cited
ALDH converts acetaldehyde to acetate.
confidence: 0.90
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited
Mitochondrial acetaldehyde dehydrogenase (ALDH) is then responsible for the further oxidation of acetaldehyde to acetate...
confidence: 0.97
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. (2009) PMID:19756185 cited
Inhibition of ALDH by cyanamide alters the effect of acetaldehyde on PPARα.
confidence: 0.80
The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants. (2007) PMID:17718394 cited
because acetaldehyde is oxidized more slowly.
confidence: 0.88