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Dopamine D2 receptor associated_with schizophrenia

Subject
Dopamine D2 receptor
Relation
associated_with
Object
schizophrenia
p-value
Evidence from: primary | all sources

Evidence (6 sources)

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. (2024) PMID:38637617 primary
DRD2 ... is a significant GWAS locus for multiple psychiatric disorders including schizophrenia.
confidence: 0.94
Evaluating historical candidate genes for schizophrenia. (2015) PMID:25754081 cited
Eight genes derived from a hypothesis about the etiology of schizophrenia ... (DRD2, ...)
confidence: 0.95
Evaluating historical candidate genes for schizophrenia. (2015) PMID:25754081 cited
The mean ratings were ≥4 for only DRD2 ... from 24 schizophrenia geneticists.
confidence: 0.85
Evaluating historical candidate genes for schizophrenia. (2015) PMID:25754081 cited
The mean ratings were ≥4 for only DRD2 ... from 24 schizophrenia geneticists.
confidence: 0.90
Evaluating historical candidate genes for schizophrenia. (2015) PMID:25754081 cited
Figure 1 shows the number of times that each gene or its protein product co-occurred with schizophrenia ... DRD2 ... increased with time.
confidence: 0.95
Evaluating historical candidate genes for schizophrenia. (2015) PMID:25754081 cited
For one of these five (DRD2), the PGC results concur.
confidence: 0.90