European ancestry associated_with alcohol dependence

Subject: European ancestry
Relation: associated_with
Object: alcohol dependence
p-value: 0.01

Evidence from: primary | all sources

Evidence (8 sources)

Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. (2013) PMID:23607416 primary

EA COGA discovery sample ... do not predict AD risk

confidence: 0.88

Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. (2013) PMID:23607416 primary

polymarker scores are nonetheless significantly associated to AD in both EA ... target samples

confidence: 0.95

Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. (2013) PMID:23607416 primary

for the EA (n = 2,763) ... study populations ... linear models for AD status

confidence: 0.90

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals. (2023) PMID:38062264 cited

in both EUR and AFR ancestries were analyzed by PGC

confidence: 0.94

Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited

individuals of European ancestry

confidence: 0.85

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015) PMID:26110981 cited

They found a significant enrichment in both ... EAs ... for association with AD in their GWAS sample ... at P≤0.01.

confidence: 0.95

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015) PMID:26110981 cited

847 AD EA cases and 552 EA controls

confidence: 0.95

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses. (2015) PMID:26110981 cited

four ontologies displayed significant enrichment in the gene sets from both EAs and AAs.

confidence: 0.80