GABA risk_factor_for alcohol dependence

Subject: GABA
Relation: risk_factor_for
Object: alcohol dependence
p-value: —

Evidence from: primary | all sources

Evidence (3 sources)

Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. (2006) PMID:17373405 primary

genes encoding parts of the receptors through which GABA acts ... may contribute to the development of alcohol dependence

confidence: 0.80

The genetics of alcohol dependence: advancing towards systems-based approaches. (2012) PMID:22854292 cited

the importance of the ... GABA ... systems in the liability to alcoholism

confidence: 0.90

Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence. (2012) PMID:22488850 cited

common risk genetic loci have been reported ... in the GABAergic system for AD

confidence: 0.95