opioid associated_with sedatives

Subject: opioid
Relation: associated_with
Object: sedatives
p-value: —

Evidence from: primary | all sources

Evidence (2 sources)

Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects. (2013) PMID:23402298 cited

Opioid side effects such as ... sedation ... are evaluated in this instrument by the patients

confidence: 0.96

Expansion of the human mu-opioid receptor gene architecture: novel functional variants. (2009) PMID:19103668 cited

Opioid analgesics ... produce significant side-effects consisting of miosis, sedation, nausea and vomiting, cognitive impairment, constipation, rapid-onset hypotension and ... respiratory depression

confidence: 0.96