paperKB
coga / coga-kb
Help
Sign in

naltrexone protective_against relapse

Subject
naltrexone
Relation
protective_against
Object
relapse
p-value
0.014
Evidence from: primary | all sources

Evidence (4 sources)

Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
NTX treatment relative to placebo led to a clinically significant reduction in relapse
confidence: 0.90
Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity. (2017) PMID:28134463 cited
A/G or G/G carriers took significantly longer to relapse (p = 0.014) than A/A carriers
confidence: 0.95
Pharmacogenetics of OPRM1. (2014) PMID:24201053 cited
Naltrexone, a MOR antagonist, is also able to reduce relapse to heavy drinking...
confidence: 0.95
Delta and kappa opioid receptor polymorphisms influence the effects of naltrexone on subjective responses to alcohol. (2012) PMID:22954510 cited
naltrexone ... increases time to first relapse and yields lower relapse rates
confidence: 0.94