IQ risk_factor_for de novo variant

Subject: IQ
Relation: risk_factor_for
Object: de novo variant
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. (2011) PMID:21658581 cited

We fit a logistic regression model with de novo CNV status for probands as the outcome and full‑scale IQ as the predictor. Odds of carrying a de novo CNV varied three‑fold across IQ levels.

confidence: 0.90