fluoxetine targets Kcnj6

Subject: fluoxetine
Relation: targets
Object: Kcnj6
p-value: —

Evidence from: primary | all sources

Evidence (1 sources)

Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. (2017) PMID:28342823 cited

Fluoxetine is an effective blocker of the Kir3.2 subunit-containing potassium channels.

confidence: 0.95