rs12914008 risk_factor_for nicotine

Subject: rs12914008
Relation: risk_factor_for
Object: nicotine
p-value: 0.035

Evidence from: primary | all sources

Evidence (1 sources)

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans. (2009) PMID:19706762 cited

In European-Americans, rs12914008 ... is associated with nicotine dependence (p = 0.035, OR = 0.73...). In the combined analysis the evidence improves (p = 0.022, OR = 0.71...).

confidence: 0.93